产品名称
Rak Rabbit Polyclonal Antibody
别名
FRK; PTK5; RAK; Tyrosine-protein kinase FRK; FYN-related kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5
蛋白名称
Tyrosine-protein kinase FRK
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2444
Human Swissprot No.
P42685
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P42685/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14302
Mouse Swissprot No.
Q922K9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q922K9
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79209
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q62662
免疫原
The antiserum was produced against synthesized peptide derived from human FRK. AA range:71-120
特异性
Rak Polyclonal Antibody detects endogenous levels of Rak protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008],
组织表达
Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.
细胞定位
Cytoplasm . Nucleus . Predominantly found in the nucleus, with a small fraction found in the cell periphery.
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
