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Rag C Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3992
产品名称
Rag C Rabbit Polyclonal Antibody
别名
RRAGC; Ras-related GTP-binding protein C; Rag C; RagC; GTPase-interacting protein 2; TIB929
类别
常规抗体
基因名称
RRAGC
蛋白名称
Ras-related GTP-binding protein C
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
64121
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64121
Human Swissprot No.
Q9HB90
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9HB90/entry
Mouse Gene ID
54170
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54170
Mouse Swissprot No.
Q99K70
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99K70
免疫原
The antiserum was produced against synthesized peptide derived from human RRAGC. AA range:302-351
特异性
Rag C Polyclonal Antibody detects endogenous levels of Rag C protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; IP 1:50-200 ELISA 2000-20000
预测分子量
44kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],
组织表达
Lymph,Ovary,
细胞定位
Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942). .
信号通路
mTOR
功能
function:Has guanine nucleotide-binding activity but weak intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.,subunit:Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HepG2, A549, and LOVO cells, using RRAGC Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HepG2 cells using RRAGC antibody.

Western Blot analysis of various cells using Rag C Polyclonal Antibody

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