产品名称
Rak Rabbit Polyclonal Antibody
别名
FRK; PTK5; RAK; Tyrosine-protein kinase FRK; FYN-related kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5
蛋白名称
Tyrosine-protein kinase FRK
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2444
Human Swissprot No.
P42685
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P42685/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14302
Mouse Swissprot No.
Q922K9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q922K9
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79209
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q62662
免疫原
The antiserum was produced against synthesized peptide derived from human FRK. AA range:71-120
特异性
Rak Polyclonal Antibody detects endogenous levels of Rak protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008],
组织表达
Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.
细胞定位
Cytoplasm . Nucleus . Predominantly found in the nucleus, with a small fraction found in the cell periphery.
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
