产品名称
Rabr Rabbit Polyclonal Antibody
别名
AGFG2; HRBL; RABR; Arf-GAP domain and FG repeat-containing protein 2; HIV-1 Rev-binding protein-like protein; Rev/Rex activation domain-binding protein related; RAB-R
蛋白名称
Arf-GAP domain and FG repeat-containing protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3268
Human Swissprot No.
O95081
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O95081/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=231801
Mouse Swissprot No.
Q80WC7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80WC7
免疫原
The antiserum was produced against synthesized peptide derived from human AGFG2. AA range:91-140
特异性
Rabr Polyclonal Antibody detects endogenous levels of Rabr protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
ArfGAP with FG repeats 2(AGFG2) Homo sapiens This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013],
组织表达
Brain,Kidney,Placenta,
功能
domain:Contains FG repeats and 4 N-P-F repeats.,similarity:Contains 1 Arf-GAP domain.,subunit:Interacts with EPS15R.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.