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Rabaptin-5β Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3948
产品名称
Rabaptin-5β Rabbit Polyclonal Antibody
别名
RABEP2; RABPT5B; Rab GTPase-binding effector protein 2; Rabaptin-5beta
类别
常规抗体
基因名称
RABEP2
蛋白名称
Rab GTPase-binding effector protein 2
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
79874
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79874
Human Swissprot No.
Q9H5N1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H5N1/entry
Mouse Gene ID
70314
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70314
Mouse Swissprot No.
Q91WG2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q91WG2
Rat Gene ID
80754
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80754
Rat Swissprot No.
Q62835
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q62835
免疫原
The antiserum was produced against synthesized peptide derived from human RABEP2. AA range:353-402
特异性
Rabaptin-5β Polyclonal Antibody detects endogenous levels of Rabaptin-5β protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
预测分子量
64kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Plays a role in membrane trafficking and in homotypic early endosome fusion.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The dimer binds RAB5A that has been activated by GTP-binding.,
组织表达
Hepatoma,Mammary gland,Testis,
细胞定位
Cytoplasm . Early endosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body .
功能
function:Plays a role in membrane trafficking and in homotypic early endosome fusion.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The dimer binds RAB5A that has been activated by GTP-binding.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HeLa, Jurkat, 293, and HUVEC cells, using RABEP2 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HeLa cells using RABEP2 antibody.

Western Blot analysis of various cells using Rabaptin-5β Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4°,overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

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