产品名称
Rab 5C Rabbit Polyclonal Antibody
别名
RAB5C; RABL; Ras-related protein Rab-5C; L1880; RAB5L
蛋白名称
Ras-related protein Rab-5C
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5878
Human Swissprot No.
P51148
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P51148/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19345
Mouse Swissprot No.
P35278
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P35278
免疫原
The antiserum was produced against synthesized peptide derived from human RAB5C. AA range:122-171
特异性
Rab 5C Polyclonal Antibody detects endogenous levels of Rab 5C protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010],
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
功能
function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Binds EEA1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
