BD-PT3934-Rab 40B Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

Rab 40B Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT3934

产品名称

Rab 40B Rabbit Polyclonal Antibody

别名

RAB40B; SEC4L; Ras-related protein Rab-40B; SOCS box-containing protein RAR; Protein Rar

类别

常规抗体

基因名称

RAB40B

蛋白名称

Ras-related protein Rab-40B

推荐应用

反应种属

Human,Rat,Mouse

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

10966

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10966

Human Swissprot No.

Q12829

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q12829/entry

Mouse Swissprot No.

Q8VHP8

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q8VHP8

免疫原

The antiserum was produced against synthesized peptide derived from human RAB40B. AA range:229-278

特异性

Rab 40B Polyclonal Antibody detects endogenous levels of Rab 40B protein.

稀释度

WB 1:500 - 1:2000. ELISA: 1:40000.. IF 1:50-200

预测分子量

34kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008],

组织表达

Brain,Hippocampus,

细胞定位

Cell membrane ; Lipid-anchor ; Cytoplasmic side .

功能

domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 1 SOCS box domain.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from Jurkat cells, using RAB40B Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of Jurkat cells using Rab 40B Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100（4°,overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.