产品名称
Rab 35 Rabbit Polyclonal Antibody
别名
RAB35; RAB1C; RAY; Ras-related protein Rab-35; GTP-binding protein RAY; Ras-related protein Rab-1C
蛋白名称
Ras-related protein Rab-35
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11021
Human Swissprot No.
Q15286
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15286/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=77407
Mouse Swissprot No.
Q6PHN9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6PHN9
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=288700
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5U316
免疫原
The antiserum was produced against synthesized peptide derived from human RAB35. AA range:99-148
特异性
Rab 35 Polyclonal Antibody detects endogenous levels of Rab 35 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Possesses GTPase activity.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
组织表达
Brain,Muscle,Uterus,
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Membrane, clathrin-coated pit . Cytoplasmic vesicle, clathrin-coated vesicle . Endosome . Melanosome . Present on sorting endosomes and recycling endosome tubules (PubMed:16950109). Tends to be enriched in PIP2-positive cell membrane domains (PubMed:16950109). During mitosis, associated with the plasma membrane and present at the ingressing furrow during early cytokinesis as well as at the intercellular bridge later during cytokinesis (PubMed:16950109). Identified in stage I to stage IV melanosomes (PubMed:17081065). .
功能
function:Possesses GTPase activity.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.