产品名称
Rab 34 Rabbit Polyclonal Antibody
别名
RAB34; RAB39; RAH; Ras-related protein Rab-34; Ras-related protein Rab-39; Ras-related protein Rah
蛋白名称
Ras-related protein Rab-34
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83871
Human Swissprot No.
Q9BZG1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BZG1/entry
Mouse Swissprot No.
Q64008
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q64008
免疫原
The antiserum was produced against synthesized peptide derived from human RAB34. AA range:206-255
特异性
Rab 34 Polyclonal Antibody detects endogenous levels of Rab 34 protein.
稀释度
WB 1:500 - 1:2000.IHC-p 1:50-200 ELISA: 1:5000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. This gene overlaps and shares exon structure with the nine-amino acid residue-repeats (NARR) gene, which encodes a functionally distinct nucleolar protein from a different reading frame. [provided by RefSeq, Jan 2012],
组织表达
Brain,Embryo,Heart,Mammary gland,Pancreas,Skeletal muscle,
细胞定位
Cytoplasm . Golgi apparatus . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Cell projection, cilium . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
功能
function:Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Associates with the Golgi complex.,subunit:Interacts with RILP.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
