产品名称
Rab 5C Rabbit Polyclonal Antibody
别名
RAB5C; RABL; Ras-related protein Rab-5C; L1880; RAB5L
蛋白名称
Ras-related protein Rab-5C
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5878
Human Swissprot No.
P51148
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P51148/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19345
Mouse Swissprot No.
P35278
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P35278
免疫原
The antiserum was produced against synthesized peptide derived from human RAB5C. AA range:122-171
特异性
Rab 5C Polyclonal Antibody detects endogenous levels of Rab 5C protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010],
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
功能
function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Binds EEA1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.