产品名称
Rab 20 Rabbit Polyclonal Antibody
别名
RAB20; Ras-related protein Rab-20
蛋白名称
Ras-related protein Rab-20
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55647
Human Swissprot No.
Q9NX57
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NX57/entry
Mouse Swissprot No.
P35295
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P35295
免疫原
The antiserum was produced against synthesized peptide derived from human RAB20. AA range:115-164
特异性
Rab 20 Polyclonal Antibody detects endogenous levels of Rab 20 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Plays a role in apical endocytosis/recycling.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules.,tissue specificity:Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).,
组织表达
Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).
细胞定位
Golgi apparatus . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
功能
function:Plays a role in apical endocytosis/recycling.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules.,tissue specificity:Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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