产品名称
Rab 18 Rabbit Polyclonal Antibody
别名
RAB18; Ras-related protein Rab-18
蛋白名称
Ras-related protein Rab-18
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22931
Human Swissprot No.
Q9NP72
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NP72/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19330
Mouse Swissprot No.
P35293
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P35293
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=307039
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5EB77
免疫原
The antiserum was produced against synthesized peptide derived from human RAB18. AA range:103-152
特异性
Rab 18 Polyclonal Antibody detects endogenous levels of Rab 18 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
细胞定位
Apical cell membrane . Lipid droplet .
功能
function:Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
