产品名称
Rab 11B Rabbit Polyclonal Antibody
别名
RAB11B; YPT3; Ras-related protein Rab-11B; GTP-binding protein YPT3
蛋白名称
Ras-related protein Rab-11B
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9230
Human Swissprot No.
Q15907
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15907/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19326
Mouse Swissprot No.
P46638
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P46638
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79434
Rat Swissprot Link
http://www.uniprot.org/uniprot/O35509
免疫原
The antiserum was produced against synthesized peptide derived from human RAB11B. AA range:164-213
特异性
Rab 11B Polyclonal Antibody detects endogenous levels of Rab 11B protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010],
组织表达
B-cell lymphoma,Brain,Cerebellum,Muscle,
细胞定位
Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus. .
功能
function:Possesses GTPase activity.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
