BD-PT3905-Ptx3 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

Ptx3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT3905

产品名称

Ptx3 Rabbit Polyclonal Antibody

别名

PTX3; TNFAIP5; TSG14; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14

类别

常规抗体

基因名称

PTX3

蛋白名称

Pentraxin-related protein PTX3

推荐应用

反应种属

Human,Mouse

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

5806

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5806

Human Swissprot No.

P26022

Human Swissprot Link

http://www.uniprot.org/uniprotkb/P26022/entry

Mouse Gene ID

19288

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19288

Mouse Swissprot No.

P48759

Mouse Swissprot Link

http://www.uniprot.org/uniprot/P48759

免疫原

The antiserum was produced against synthesized peptide derived from human PTX3. AA range:1-50

特异性

Ptx3 Polyclonal Antibody detects endogenous levels of Ptx3 protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

预测分子量

40kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016],

组织表达

Brain,Endothelial cell,Foreskin,

细胞定位

Secreted.

功能

function:Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.,induction:By interleukin-1 beta and TNF-alpha.,PTM:Glycosylated.,similarity:Contains 1 pentaxin domain.,subunit:Homooctamer; disulfide-linked. Binds to C1q.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of HUVEC cells, using PTX3 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from 293 cells, using PTX3 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using Ptx3 Polyclonal Antibody diluted at 1：1000

Immunohistochemical analysis of paraffin-embedded Human colon. 1, Antibody was diluted at 1:100（4°,overnight）. 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200（room temperature, 30min）.