BD-PT3903

PTPζ Rabbit Polyclonal Antibody

PTPRZ1; HTPZP2; PTPRZ; PTPRZ2; PTPZ; Receptor-type tyrosine-protein phosphatase zeta; R-PTP-zeta; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta-2

常规抗体

PTPRZ1

Receptor-type tyrosine-protein phosphatase zeta

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

5803

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5803

P23471

http://www.uniprot.org/uniprotkb/P23471/entry

25613

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25613

Q62656

http://www.uniprot.org/uniprot/Q62656

The antiserum was produced against synthesized peptide derived from human PTPRZ1. AA range:122-171

PTPζ Polyclonal Antibody detects endogenous levels of PTPζ protein.

WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

250kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011],

Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain.

[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Secreted . A secreted form is apparently generated by shedding of the extracellular domain. .; [Isoform 2]: Secreted .

Epithelial cell signaling in Helicobacter pylori infection;

catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,caution:PubMed:8387522 and PubMed:2170109 have termed this protein RPTPase beta.,function:May be involved in the regulation of specific developmental processes in the CNS.,sequence caution:Contaminating sequence. The N-terminus may be contaminated with vector sequence.,similarity:Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.,similarity:Contains 1 alpha-carbonic anhydrase domain.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 2 tyrosine-protein phosphatase domains.,subunit:The carbonic-anhydrase like domain binds to contactin.,tissue specificity:Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.