BD-PT3886

PSMD11 Rabbit Polyclonal Antibody

PSMD11; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5

常规抗体

PSMD11

26S proteasome non-ATPase regulatory subunit 11

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

5717

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5717

O00231

http://www.uniprot.org/uniprotkb/O00231/entry

69077

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69077

Q8BG32

http://www.uniprot.org/uniprot/Q8BG32

The antiserum was produced against synthesized peptide derived from human PSMD11. AA range:271-320

PSMD11 Polyclonal Antibody detects endogenous levels of PSMD11 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

42kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq,

Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate.

Nucleus . Cytoplasm, cytosol .

Proteasome;

function:Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.,similarity:Belongs to the proteasome subunit S9 family.,similarity:Contains 1 PCI domain.,subunit:Component of the PA700 complex.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.