BD-PT3885

PSMC6 Rabbit Polyclonal Antibody

PSMC6; SUG2; 26S protease regulatory subunit 10B; 26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42

常规抗体

PSMC6

26S protease regulatory subunit 10B

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

5706

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5706

P62333

http://www.uniprot.org/uniprotkb/P62333/entry

67089

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67089

P62334

http://www.uniprot.org/uniprot/P62334

The antiserum was produced against synthesized peptide derived from human PSMC6. AA range:61-110

PSMC6 Polyclonal Antibody detects endogenous levels of PSMC6 protein.

WB 1:500-2000;IHC-p 1:50-300

44kD

-20°C/1 year

Polyclonal, Rabbit,IgG

proteasome 26S subunit, ATPase 6(PSMC6) Homo sapiens The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chrom

Aorta,Urinary bladder,

Cytoplasm . Nucleus .

Proteasome;

function:The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.,similarity:Belongs to the AAA ATPase family.,subunit:Found in the multi-protein complexes: the 26S proteasome (formed from the 20S proteasome and PA700), and the modulator. PA700 consists of 28 subunits arranged to form a cylinder-shaped complex by four stacked rings, each containing seven subunits. Interacts with PAAF1.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.