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PSK2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3882
产品名称
PSK2 Rabbit Polyclonal Antibody
别名
TAOK1; KIAA1361; MAP3K16; MARKK; Serine/threonine-protein kinase TAO1; Kinase from chicken homolog B; hKFC-B; MARK Kinase; MARKK; Prostate-derived sterile 20-like kinase 2; PSK-2; PSK2; Prostate-derived STE20-like kinase 2; Thousand and one
类别
常规抗体
基因名称
TAOK1
蛋白名称
Serine/threonine-protein kinase TAO1
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
57551
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57551
Human Swissprot No.
Q7L7X3
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q7L7X3/entry
Mouse Gene ID
216965
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=216965
Mouse Swissprot No.
Q5F2E8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5F2E8
Rat Gene ID
286993
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=286993
Rat Swissprot No.
O88664
Rat Swissprot Link
http://www.uniprot.org/uniprot/O88664
免疫原
The antiserum was produced against synthesized peptide derived from human TAOK1. AA range:431-480
特异性
PSK2 Polyclonal Antibody detects endogenous levels of PSK2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
预测分子量
120kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Self-associates. Interacts with MKK3.,tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.,
组织表达
Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.
细胞定位
Cytoplasm .
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Self-associates. Interacts with MKK3.,tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TAOK1 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from NIH/3T3 cells, using TAOK1 Antibody. The lane on the right is blocked with the synthesized peptide.

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