BD-PT3881

PSGR Rabbit Polyclonal Antibody

OR51E2; PSGR; Olfactory receptor 51E2; HPRAJ; Olfactory receptor OR11-16; Prostate-specific G-protein coupled receptor

常规抗体

OR51E2

Olfactory receptor 51E2

WB

Human,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

81285

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81285

Q9H255

http://www.uniprot.org/uniprotkb/Q9H255/entry

170816

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170816

O88628

http://www.uniprot.org/uniprot/O88628

The antiserum was produced against synthesized peptide derived from human OR51E2. AA range:221-270

PSGR Polyclonal Antibody detects endogenous levels of PSGR protein.

WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

35kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008],

Highly expressed in the prostate (PubMed:11707321). Also expressed in spleen, liver, olfactory epithelium, retinal pigment epithelium and medulla oblongata (PubMed:29249973, PubMed:11707321, PubMed:16491480). In the retinal pigment epithelium expression is restricted to the pigment cells and choroid (at protein level) (PubMed:29249973). Expressed in epidermal melanocytes (at protein level) (PubMed:27226631).

Cell membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein .

Olfactory transduction;

function:Odorant receptor .,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Exclusively expressed in the prostate. Up-regulated in prostate cancers.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.