产品名称
PRX1 Rabbit Polyclonal Antibody
别名
PRRX1; PMX1; Paired mesoderm homeobox protein 1; Homeobox protein PHOX1; Paired-related homeobox protein 1; PRX-1
蛋白名称
Paired mesoderm homeobox protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5396
Human Swissprot No.
P54821
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P54821/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18933
Mouse Swissprot No.
P63013
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P63013
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=266813
Rat Swissprot Link
http://www.uniprot.org/uniprot/P63014
免疫原
Synthesized peptide derived from PRX1 . at AA range: 30-110
特异性
PRX1 Polyclonal Antibody detects endogenous levels of PRX1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008],
功能
function:Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer.,similarity:Belongs to the paired homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 OAR domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.