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PRX1 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3874
产品名称
PRX1 Rabbit Polyclonal Antibody
别名
PRRX1; PMX1; Paired mesoderm homeobox protein 1; Homeobox protein PHOX1; Paired-related homeobox protein 1; PRX-1
类别
常规抗体
基因名称
PRRX1
蛋白名称
Paired mesoderm homeobox protein 1
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
5396
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5396
Human Swissprot No.
P54821
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P54821/entry
Mouse Gene ID
18933
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18933
Mouse Swissprot No.
P63013
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P63013
Rat Gene ID
266813
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=266813
Rat Swissprot No.
P63014
Rat Swissprot Link
http://www.uniprot.org/uniprot/P63014
免疫原
Synthesized peptide derived from PRX1 . at AA range: 30-110
特异性
PRX1 Polyclonal Antibody detects endogenous levels of PRX1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
预测分子量
27kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus.
功能
function:Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer.,similarity:Belongs to the paired homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 OAR domain.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western Blot analysis of various cells using PRX1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

Western Blot analysis of Jurkat cells using PRX1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

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