产品名称
PRPH Rabbit Polyclonal Antibody
别名
PRPH; NEF4; PRPH1; Peripherin; Neurofilament 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5630
Human Swissprot No.
P41219
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P41219/entry
Mouse Swissprot No.
P15331
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P15331
Rat Swissprot Link
http://www.uniprot.org/uniprot/P21807
免疫原
The antiserum was produced against synthesized peptide derived from human Peripherin. AA range:421-470
特异性
PRPH Polyclonal Antibody detects endogenous levels of PRPH protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008],
组织表达
Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells.
细胞定位
Cytoplasm, cytoskeleton . Cell projection, axon . Perikaryon .
信号通路
Amyotrophic lateral sclerosis (ALS);
功能
function:Class-III neuronal intermediate filament protein.,online information:Peripherin entry,similarity:Belongs to the intermediate filament family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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