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PREP-2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3855
产品名称
PREP-2 Rabbit Polyclonal Antibody
别名
PKNOX2; PREP2; Homeobox protein PKNOX2; Homeobox protein PREP-2; PBX/knotted homeobox 2
类别
常规抗体
基因名称
PKNOX2
蛋白名称
Homeobox protein PKNOX2
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
63876
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=63876
Human Swissprot No.
Q96KN3
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96KN3/entry
Mouse Gene ID
208076
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=208076
Mouse Swissprot No.
Q8BG99
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BG99
免疫原
The antiserum was produced against synthesized peptide derived from human PKNOX2. AA range:341-390
特异性
PREP-2 Polyclonal Antibody detects endogenous levels of PREP-2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
预测分子量
55kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).[supplied by OMIM, Oct 2009],
组织表达
Brain,Small intestine,
细胞定位
Nucleus .
功能
similarity:Belongs to the TALE/MEIS homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HepG2 cells, using PKNOX2 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using PREP-2 Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4°,overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

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