产品名称
Prefoldin 1 Rabbit Polyclonal Antibody
别名
PFDN1; PFD1; Prefoldin subunit 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5201
Human Swissprot No.
O60925
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O60925/entry
Mouse Swissprot No.
Q9CWM4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CWM4
免疫原
The antiserum was produced against synthesized peptide derived from human PFDN1. AA range:1-50
特异性
Prefoldin 1 Polyclonal Antibody detects endogenous levels of Prefoldin 1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008],
功能
function:Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.,similarity:Belongs to the prefoldin subunit beta family.,subunit:Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
