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PKI β Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3776
产品名称
PKI β Rabbit Polyclonal Antibody
别名
PKIB; PRKACN2; cAMP-dependent protein kinase inhibitor beta; PKI-beta
类别
常规抗体
基因名称
PKIB
蛋白名称
cAMP-dependent protein kinase inhibitor beta
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
5570
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5570
Human Swissprot No.
Q9C010
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9C010/entry
Mouse Swissprot No.
Q04758
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q04758
Rat Swissprot No.
P27775
Rat Swissprot Link
http://www.uniprot.org/uniprot/P27775
免疫原
The antiserum was produced against synthesized peptide derived from human IPKB. AA range:29-78
特异性
PKI β Polyclonal Antibody detects endogenous levels of PKI β protein.
稀释度
IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000,WB 1:500-2000
参考分子量
8kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
protein kinase (cAMP-dependent, catalytic) inhibitor beta(PKIB) Homo sapiens This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
组织表达
Placenta,
细胞定位
nucleus,cytoplasm,
功能
function:Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.,similarity:Belongs to the PKI family.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of MCF7 cells, using IPKB Antibody. The picture on the right is blocked with the synthesized peptide.

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