产品名称
PKI β Rabbit Polyclonal Antibody
别名
PKIB; PRKACN2; cAMP-dependent protein kinase inhibitor beta; PKI-beta
蛋白名称
cAMP-dependent protein kinase inhibitor beta
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5570
Human Swissprot No.
Q9C010
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9C010/entry
Mouse Swissprot No.
Q04758
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q04758
Rat Swissprot Link
http://www.uniprot.org/uniprot/P27775
免疫原
The antiserum was produced against synthesized peptide derived from human IPKB. AA range:29-78
特异性
PKI β Polyclonal Antibody detects endogenous levels of PKI β protein.
稀释度
IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000,WB 1:500-2000
宿主
Polyclonal, Rabbit,IgG
背景介绍
protein kinase (cAMP-dependent, catalytic) inhibitor beta(PKIB) Homo sapiens This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
功能
function:Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.,similarity:Belongs to the PKI family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.