产品名称
PITPβ Rabbit Polyclonal Antibody
别名
PITPNB; Phosphatidylinositol transfer protein beta isoform; PI-TP-beta; PtdIns transfer protein beta; PtdInsTP beta
蛋白名称
Phosphatidylinositol transfer protein beta isoform
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23760
Human Swissprot No.
P48739
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P48739/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56305
Mouse Swissprot No.
P53811
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P53811
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114561
Rat Swissprot Link
http://www.uniprot.org/uniprot/P53812
免疫原
The antiserum was produced against synthesized peptide derived from human PITPNB. AA range:20-69
特异性
PITPβ Polyclonal Antibody detects endogenous levels of PITPβ protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013],
组织表达
Widely expressed in various tissues including brain.
细胞定位
Golgi apparatus . Golgi apparatus membrane . Endoplasmic reticulum membrane .
功能
function:Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.,PTM:Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting.,similarity:Belongs to the PtdIns transfer protein family. Class I subfamily.,tissue specificity:Widely expressed in various tissues including brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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