产品名称
PHF3 Rabbit Polyclonal Antibody
别名
PHF3; KIAA0244; PHD finger protein 3
蛋白名称
PHD finger protein 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23469
Human Swissprot No.
Q92576
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q92576/entry
免疫原
The antiserum was produced against synthesized peptide derived from human PHF3. AA range:1990-2039
特异性
PHF3 Polyclonal Antibody detects endogenous levels of PHF3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
组织表达
Ubiquitous. Expression is significantly reduced or lost in glioblastomas, glioblastoma cell lines, anaplastic astrocytomas, and astrocytomas.
功能
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 TFIIS central domain.,tissue specificity:Ubiquitous. Expression is significantly reduced or lost in glioblastomas, glioblastoma cell lines, anaplastic astrocytomas, and astrocytomas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.