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PHF3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3698
产品名称
PHF3 Rabbit Polyclonal Antibody
别名
PHF3; KIAA0244; PHD finger protein 3
类别
常规抗体
基因名称
PHF3
蛋白名称
PHD finger protein 3
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
23469
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23469
Human Swissprot No.
Q92576
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q92576/entry
免疫原
The antiserum was produced against synthesized peptide derived from human PHF3. AA range:1990-2039
特异性
PHF3 Polyclonal Antibody detects endogenous levels of PHF3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
预测分子量
230kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
组织表达
Ubiquitous. Expression is significantly reduced or lost in glioblastomas, glioblastoma cell lines, anaplastic astrocytomas, and astrocytomas.
功能
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 TFIIS central domain.,tissue specificity:Ubiquitous. Expression is significantly reduced or lost in glioblastomas, glioblastoma cell lines, anaplastic astrocytomas, and astrocytomas.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PHF3 Antibody. The picture on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using PHF3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

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