产品名称
PHAPI2 Rabbit Polyclonal Antibody
别名
ANP32B; APRIL; PHAPI2; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29
蛋白名称
Acidic leucine-rich nuclear phosphoprotein 32 family member B
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10541
Human Swissprot No.
Q92688
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q92688/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67628
Mouse Swissprot No.
Q9EST5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9EST5
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170724
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q9EST6
免疫原
The antiserum was produced against synthesized peptide derived from human ANP32B. AA range:1-50
特异性
PHAPI2 Polyclonal Antibody detects endogenous levels of PHAPI2 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity.,similarity:Belongs to the ANP32 family.,similarity:Contains 4 LRR (leucine-rich) repeats.,subcellular location:Accumulates in the nuclei at the S phase.,tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.,
组织表达
Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.
细胞定位
[Isoform 1]: Nucleus . Cytoplasm . Accumulates in the nuclei at the S phase. .; [Isoform 2]: Cytoplasm. Lacks a nuclear localization signal.
功能
function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity.,similarity:Belongs to the ANP32 family.,similarity:Contains 4 LRR (leucine-rich) repeats.,subcellular location:Accumulates in the nuclei at the S phase.,tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
