产品名称
PHACTR4 Rabbit Polyclonal Antibody
别名
PHACTR4; Phosphatase and actin regulator 4
蛋白名称
Phosphatase and actin regulator 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=65979
Human Swissprot No.
Q8IZ21
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8IZ21/entry
Mouse Swissprot No.
Q501J7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q501J7
免疫原
The antiserum was produced against synthesized peptide derived from human PHACTR4. AA range:363-412
特异性
PHACTR4 Polyclonal Antibody detects endogenous levels of PHACTR4 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Adrenal cortex,Fetal brain,Fetal liver,Skin,Testis,
细胞定位
Cytoplasm . Cell projection, lamellipodium .
功能
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the phosphatase and actin regulator family.,similarity:Contains 3 RPEL repeats.,subunit:Binds PPP1CA and actin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
