BD-PT3688-PGD Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

PGD Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT3688

产品名称

PGD Rabbit Polyclonal Antibody

别名

PGD; PGDH; 6-phosphogluconate dehydrogenase; decarboxylating

类别

常规抗体

基因名称

PGD

蛋白名称

6-phosphogluconate dehydrogenase decarboxylating

推荐应用

反应种属

Human,Mouse,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

5226

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5226

Human Swissprot No.

P52209

Human Swissprot Link

http://www.uniprot.org/uniprotkb/P52209/entry

Mouse Gene ID

110208

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=110208

Mouse Swissprot No.

Q9DCD0

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q9DCD0

Rat Gene ID

100360000

Rat Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100360180

Rat Swissprot No.

P85968

Rat Swissprot Link

http://www.uniprot.org/uniprot/P85968

免疫原

The antiserum was produced against synthesized peptide derived from human PGD. AA range:71-120

特异性

PGD Polyclonal Antibody detects endogenous levels of PGD protein.

稀释度

IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:5000.. IF 1:50-200

预测分子量

40kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],

组织表达

Heart,Lung,

细胞定位

Cytoplasm .

信号通路

Pentose phosphate pathway;Glutathione metabolism;

功能

catalytic activity:6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.,similarity:Belongs to the 6-phosphogluconate dehydrogenase family.,subunit:Homodimer.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western Blot analysis of A549 cells using PGD Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human colon. 1, Antibody was diluted at 1:100（4°,overnight）. 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200（room temperature, 30min）.

Immunohistochemical analysis of paraffin-embedded Human Right kidney. 1, Antibody was diluted at 1:400（4°,overnight）. 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200（room temperature, 30min）.