产品名称
B3GN8 Rabbit Polyclonal Antibody
基因名称
B3GNT8 B3GALT7 BGALT15
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/374907
Human Swissprot No.
Q7Z7M8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7Z7M8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/232984
Mouse Swissprot No.
Q8R3I9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R3I9
免疫原
Synthesized peptide derived from human B3GN8 AA range: 218-268
特异性
This antibody detects endogenous levels of B3GN8 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Highly expressed in small intestine, pancreas, spleen, bone marrow, lung, throat, and ileum, and weakly in fetal brain, cerebellum, heart, liver, tongue, breast, uteri, and testis. Not detected in colon. Differentially expressed in human tumor cell lines.
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
功能
function:Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans.,induction:Up-regulated in colon cancer.,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family.,subunit:Forms a complex of enhanced enzymatic activity with B3GNT2 in vitro.,tissue specificity:Highly expressed in small intestine, pancreas, spleen, bone marrow, lung, throat, and ileum, and weakly in fetal brain, cerebellum, heart, liver, tongue, breast, uteri, and testis. Not detected in colon. Differentially expressed in human tumor cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
