产品名称
PEPT1 Rabbit Polyclonal Antibody
别名
SLC15A1; PEPT1; Solute carrier family 15 member 1; Intestinal H(+)/peptide cotransporter; Oligopeptide transporter; small intestine isoform; Peptide transporter 1
蛋白名称
Solute carrier family 15 member 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6564
Human Swissprot No.
P46059
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P46059/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56643
Mouse Swissprot No.
Q9JIP7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JIP7
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=117261
Rat Swissprot Link
http://www.uniprot.org/uniprot/P51574
免疫原
The antiserum was produced against synthesized peptide derived from human SLC15A1. AA range:225-274
特异性
PEPT1 Polyclonal Antibody detects endogenous levels of PEPT1 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. [provided by RefSeq, Apr 2010],
组织表达
Intestine,PCR rescued clones,
细胞定位
Membrane ; Multi-pass membrane protein .
功能
function:Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products.,similarity:Belongs to the PTR2/POT transporter (TC 2.A.17) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.