BD-PT3609-PBF Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

PBF Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT3609

产品名称

PBF Rabbit Polyclonal Antibody

别名

PTTG1IP; C21orf1; C21orf3; Pituitary tumor-transforming gene 1 protein-interacting protein; Pituitary tumor-transforming gene protein-binding factor; PBF; PTTG-binding factor

类别

常规抗体

基因名称

PTTG1IP

蛋白名称

Pituitary tumor-transforming gene 1 protein-interacting protein

推荐应用

反应种属

Human,Mouse,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

754

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=754

Human Swissprot No.

P53801

Human Swissprot Link

http://www.uniprot.org/uniprotkb/P53801/entry

Mouse Gene ID

108705

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=108705

Mouse Swissprot No.

Q8R143

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q8R143

Rat Gene ID

365548

Rat Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=365548

Rat Swissprot No.

Q6P767

Rat Swissprot Link

http://www.uniprot.org/uniprot/Q6P767

免疫原

The antiserum was produced against synthesized peptide derived from human PTTG. AA range:116-165

特异性

PBF Polyclonal Antibody detects endogenous levels of PBF protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

预测分子量

20kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013],

组织表达

Ubiquitous.

细胞定位

Membrane ; Single-pass type I membrane protein . Cytoplasm . Nucleus . According to PubMed:10781616, it is found in the cytoplasm and the nucleus.

信号通路

Cell Cycle

功能

function:May facilitate PTTG1 nuclear translocation.,induction:By transcription factor RUNX2.,subcellular location:According to PubMed:10781616 it is found in the cytoplasm and the nucleus.,subunit:Interacts with PTTG1.,tissue specificity:Ubiquitous.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PTTG Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from RAW264.7 cells, using PTTG Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HeLa cells using PTTG antibody.

Immunohistochemical analysis of paraffin-embedded Human Right kidney. 1, Antibody was diluted at 1:100（4°,overnight）. 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200（room temperature, 30min）.