产品名称
Pax-1 Rabbit Polyclonal Antibody
别名
PAX1; HUP48; Paired box protein Pax-1; HuP48
蛋白名称
Paired box protein Pax-1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5075
Human Swissprot No.
P15863
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P15863/entry
Mouse Swissprot No.
P09084
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P09084
免疫原
The antiserum was produced against synthesized peptide derived from human Pax-1. AA range:318-367
特异性
Pax-1 Polyclonal Antibody detects endogenous levels of Pax-1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012],
功能
function:This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column.,similarity:Contains 1 paired domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
