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PABP3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3563
产品名称
PABP3 Rabbit Polyclonal Antibody
别名
PABPC3; PABP3; PABPL3; Polyadenylate-binding protein 3; PABP-3; Poly(A)-binding protein 3; Testis-specific poly(A)-binding protein
类别
常规抗体
基因名称
PABPC3
蛋白名称
Polyadenylate-binding protein 3
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
5042
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5042
Human Swissprot No.
Q9H361
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H361/entry
免疫原
The antiserum was produced against synthesized peptide derived from human PABPC3. AA range:352-401
特异性
PABP3 Polyclonal Antibody detects endogenous levels of PABP3 protein.
稀释度
WB 1:500 - 1:2000.IHC-p:1:50-300 ELISA: 1:20000.. IF 1:50-200
预测分子量
70kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002],
组织表达
Testis specific.
细胞定位
Cytoplasm .
功能
function:Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.,similarity:Belongs to the polyadenylate-binding protein type-1 family.,similarity:Contains 1 PABC domain.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Testis specific.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of PABPC3 Antibody. The lane on the right is blocked with the PABPC3 peptide.

Immunohistochemistryt analysis of paraffin-embedded human testis, using PABPC3 Antibody. The lane on the right is blocked with the PABPC3 peptide.

Western Blot analysis of 3T3 cells using PABP3 Polyclonal Antibody

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