产品名称
p44S10 Rabbit Polyclonal Antibody
别名
PSMD6; KIAA0107; PFAAP4; 26S proteasome non-ATPase regulatory subunit 6; 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; Phosphonoformate immuno-associated protein 4;
蛋白名称
26S proteasome non-ATPase regulatory subunit 6
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9861
Human Swissprot No.
Q15008
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15008/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66413
Mouse Swissprot No.
Q99JI4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99JI4
免疫原
The antiserum was produced against synthesized peptide derived from human PSMD6. AA range:201-250
特异性
p44S10 Polyclonal Antibody detects endogenous levels of p44S10 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012],
组织表达
Bone marrow,Lymph,Mammary cancer,Ovary,Placenta,Testis,
细胞定位
proteasome complex,nucleoplasm,cytosol,proteasome regulatory particle,proteasome accessory complex,extracellular exosome,
功能
function:Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.,similarity:Belongs to the proteasome subunit S10 family.,similarity:Contains 1 PCI domain.,subunit:Component of the PA700 complex.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
