BD-PT3515-p39 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

p39 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT3515

产品名称

p39 Rabbit Polyclonal Antibody

别名

CDK5R2; NCK5AI; Cyclin-dependent kinase 5 activator 2; CDK5 activator 2; Cyclin-dependent kinase 5 regulatory subunit 2; p39; p39I

类别

常规抗体

基因名称

CDK5R2

蛋白名称

Cyclin-dependent kinase 5 activator 2

推荐应用

反应种属

Human,Rat,Mouse

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

8941

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8941

Human Swissprot No.

Q13319

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q13319/entry

Mouse Swissprot No.

O35926

Mouse Swissprot Link

http://www.uniprot.org/uniprot/O35926

免疫原

The antiserum was produced against synthesized peptide derived from human CDK5R2. AA range:81-130

特异性

p39 Polyclonal Antibody detects endogenous levels of p39 protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

预测分子量

40kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008],

组织表达

Brain and neuron specific.

细胞定位

Cell membrane ; Lipid-anchor ; Cytoplasmic side .

功能

function:Activator of CDK5/TPKII.,similarity:Belongs to the cyclin-dependent kinase 5 activator family.,subunit:Heterodimer of a catalytic subunit and a regulatory subunit.,tissue specificity:Brain and neuron specific.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HUVEC cells, using CDK5R2 Antibody. The lane on the right is blocked with the synthesized peptide.

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100（4° overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.

Western Blot analysis of various cells using p39 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.