产品名称
P2RY8 Rabbit Polyclonal Antibody
别名
P2RY8; P2Y purinoceptor 8; P2Y8
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=286530
Human Swissprot No.
Q86VZ1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86VZ1/entry
免疫原
The antiserum was produced against synthesized peptide derived from human P2RY8. AA range:192-241
特异性
P2RY8 Polyclonal Antibody detects endogenous levels of P2RY8 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
purinergic receptor P2Y8(P2RY8) Homo sapiens The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008],
组织表达
Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Probable receptor for purines coupled to G-proteins.,induction:Down-regulated during granulocytic regulation.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
