产品名称
OTUB2 Rabbit Polyclonal Antibody
别名
OTUB2; C14orf137; OTB2; OTU2; Ubiquitin thioesterase OTUB2; Deubiquitinating enzyme OTUB2; OTU domain-containing ubiquitin aldehyde-binding protein 2; Otubain-2; Ubiquitin-specific-processing protease OTUB2
蛋白名称
Ubiquitin thioesterase OTUB2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=78990
Human Swissprot No.
Q96DC9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96DC9/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68149
Mouse Swissprot No.
Q9CQX0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CQX0
免疫原
The antiserum was produced against synthesized peptide derived from human OTUB2. AA range:133-182
特异性
OTUB2 Polyclonal Antibody detects endogenous levels of OTUB2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
OTU deubiquitinase, ubiquitin aldehyde binding 2(OTUB2) Homo sapiens This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. [provided by RefSeq, Aug 2011],
组织表达
Widely expressed. Expressed at higher level in brain.
功能
function:Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.,similarity:Belongs to the peptidase C65 family.,similarity:Contains 1 OTU domain.,tissue specificity:Widely expressed. Expressed at higher level in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
