产品名称
Olfactory receptor 8G1 Rabbit Polyclonal Antibody
别名
OR8G1; OR8G1P; Olfactory receptor 8G1; Olfactory receptor OR11-281; Olfactory receptor TPCR25
蛋白名称
Olfactory receptor 8G1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26494
Human Swissprot No.
Q15617
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15617/entry
免疫原
The antiserum was produced against synthesized peptide derived from human OR8G1. AA range:262-311
特异性
Olfactory receptor 8G1 Polyclonal Antibody detects endogenous levels of Olfactory receptor 8G1 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This family member represents a polymorphic pseudogene, whereby some individuals have a functional allele that encodes a full-length protein, while others have a non-functional allele due to t
细胞定位
Cell membrane; Multi-pass membrane protein.
功能
function:Odorant receptor .,polymorphism:A stop codon in the gene coding for this protein at position Tyr-259 is responsible for functional diversity thus producing thus a pseudogene.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
