产品名称
Olfactory receptor 6Q1 Rabbit Polyclonal Antibody
别名
OR6Q1; Olfactory receptor 6Q1; Olfactory receptor OR11-226
蛋白名称
Olfactory receptor 6Q1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=219952
Human Swissprot No.
Q8NGQ2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8NGQ2/entry
免疫原
The antiserum was produced against synthesized peptide derived from human OR6Q1. AA range:23-72
特异性
Olfactory receptor 6Q1 Polyclonal Antibody detects endogenous levels of Olfactory receptor 6Q1 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Olfactory transduction;
功能
function:Odorant receptor .,polymorphism:A single nucleotide deletion at position Leu-229 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene. The deletion is more frequent in African-Americans than in non-Africans.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
