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Olfactory receptor 5AR1 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT3395
产品名称
Olfactory receptor 5AR1 Rabbit Polyclonal Antibody
别名
OR5AR1; Olfactory receptor 5AR1; Olfactory receptor OR11-209
类别
常规抗体
基因名称
OR5AR1
蛋白名称
Olfactory receptor 5AR1
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
219493
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=219493
Human Swissprot No.
Q8NGP9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8NGP9/entry
免疫原
The antiserum was produced against synthesized peptide derived from human OR5AR1. AA range:239-288
特异性
Olfactory receptor 5AR1 Polyclonal Antibody detects endogenous levels of Olfactory receptor 5AR1 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
预测分子量
35kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Olfactory transduction;
功能
function:Odorant receptor .,polymorphism:A stop codon in the gene coding for this protein at position Gln-19 is responsible for functional diversity thus producing a pseudogene.,similarity:Belongs to the G-protein coupled receptor 1 family.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of A549 cells, using OR5AR1 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from Jurkat, COLO, and MCF-7 cells, using OR5AR1 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HepG2 cells using OR5AR1 antibody.

Western Blot analysis of Jurkat cells using Olfactory receptor 5AR1 Polyclonal Antibody

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