产品名称
OGCP Rabbit Polyclonal Antibody
别名
SLC25A11; SLC20A4; Mitochondrial 2-oxoglutarate/malate carrier protein; OGCP; Solute carrier family 25 member 11
蛋白名称
Mitochondrial 2-oxoglutarate/malate carrier protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8402
Human Swissprot No.
Q02978
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q02978/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67863
Mouse Swissprot No.
Q9CR62
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CR62
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64201
Rat Swissprot Link
http://www.uniprot.org/uniprot/P97700
免疫原
The antiserum was produced against synthesized peptide derived from human SLC25A11. AA range:132-181
特异性
OGCP Polyclonal Antibody detects endogenous levels of OGCP protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).[supplied by OMIM, Jan 2011],
组织表达
B-cell lymphoma,Brain,Muscle,Tongue,Uterus,
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .
功能
function:Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
