产品名称
ODC Rabbit Polyclonal Antibody
别名
SLC25A21; ODC; Mitochondrial 2-oxodicarboxylate carrier; Solute carrier family 25 member 21
蛋白名称
Mitochondrial 2-oxodicarboxylate carrier
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=89874
Human Swissprot No.
Q9BQT8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BQT8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=217593
Mouse Swissprot No.
Q8BZ09
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BZ09
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=171151
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q99JD3
免疫原
The antiserum was produced against synthesized peptide derived from human SLC25A21. AA range:134-183
特异性
ODC Polyclonal Antibody detects endogenous levels of ODC protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004],
组织表达
Expressed in placenta, gall bladder and colon.
细胞定位
Mitochondrion inner membrane; Multi-pass membrane protein.
功能
function:Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
