BD-PK0004-Acetyl Histone H2B (K12) Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

Acetyl Histone H2B (K12) Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PK0004

产品名称

Acetyl Histone H2B (K12) Rabbit Polyclonal Antibody

别名

H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s

类别

常规抗体

基因名称

H2BFS

蛋白名称

Histone H2B type F-S

推荐应用

反应种属

Human,Mouse,Monkey

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

54145

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54145

Human Swissprot No.

P57053

Human Swissprot Link

http://www.uniprot.org/uniprotkb/P57053/entry

免疫原

The antiserum was produced against synthesized peptide derived from human Histone H2B around the acetylated site of Lys12. AA range:10-59

特异性

Acetyl-Histone H2B (K12) Polyclonal Antibody detects endogenous levels of Histone H2B protein only when acetylated at K12.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

预测分子量

14kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

H2BFS (H2B Histone Family Member S (Pseudogene)) is a Pseudogene. Diseases associated with H2BFS include?endometrial stromal sarcoma. Among its related pathways are?Packaging Of Telomere Ends. GO annotations related to this gene include?sequence-specific DNA binding?and?protein heterodimerization activity. An important paralog of this gene is?HIST1H2BH.

细胞定位

Nucleus. Chromosome.

信号通路

Protein_Acetylation

功能

DNA packaging,?chromatin organization,?chromatin assembly or disassembly,?nucleosome assembly,?defense response,?response to bacterium,?chromatin assembly,?cellular macromolecular complex subunit organization,?cellular macromolecular complex assembly,?nucleosome organization,?defense response to bacterium,?macromolecular complex subunit organization,?chromosome organization,?macromolecular complex assembly,?protein-DNA complex assembly,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of HeLa cells, using Histone H2B （Acetyl-Lys12） Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Histone H2B （Acetyl-Lys12） Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from COS7 cells, treated with TSA 400nM 24h, using Histone H2B （Acetyl-Lys12） Antibody. The lane on the right is blocked with the synthesized peptide.