产品名称
OATP1 Rabbit Polyclonal Antibody
别名
SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3; Solute carrier organic anion transporter family member 1A2; OATP-A; Organic anion-transporting polypeptide 1; OATP-1; Sodium-independent organic anion transporter; Solute carrier family 21 member 3
蛋白名称
Solute carrier organic anion transporter family member 1A2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6579
Human Swissprot No.
P46721
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P46721/entry
免疫原
The antiserum was produced against synthesized peptide derived from human SLCO1A2. AA range:251-300
特异性
OATP1 Polyclonal Antibody detects endogenous levels of OATP1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008],
组织表达
Brain,Liver,Teratocarcinoma,
细胞定位
Cell membrane; Multi-pass membrane protein.
功能
function:Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids.,similarity:Belongs to the organo anion transporter (TC 2.A.60) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
