产品名称
NTR1 Rabbit Polyclonal Antibody
别名
NTSR1; NTRR; Neurotensin receptor type 1; NT-R-1; NTR1; High-affinity levocabastine-insensitive neurotensin receptor; NTRH
蛋白名称
Neurotensin receptor type 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4923
Human Swissprot No.
P30989
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P30989/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18216
Mouse Swissprot No.
O88319
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88319
免疫原
The antiserum was produced against synthesized peptide derived from human NTR1. AA range:181-230
特异性
NTR1 Polyclonal Antibody detects endogenous levels of NTR1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008],
组织表达
Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.
细胞定位
Cell membrane ; Multi-pass membrane protein . Membrane raft . Palmitoylation is required for localization at CAV1-enriched membrane rafts. .
信号通路
Calcium;Neuroactive ligand-receptor interaction;
功能
function:Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Neurotensin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
