产品名称
NTF2 Rabbit Polyclonal Antibody
别名
NUTF2; NTF2; Nuclear transport factor 2; NTF-2; Placental protein 15; PP15
蛋白名称
Nuclear transport factor 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10204
Human Swissprot No.
P61970
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P61970/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=621832
Mouse Swissprot No.
P61971
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P61971
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=291981
Rat Swissprot Link
http://www.uniprot.org/uniprot/P61972
免疫原
The antiserum was produced against synthesized peptide derived from human NUTF2. AA range:67-116
特异性
NTF2 Polyclonal Antibody detects endogenous levels of NTF2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016],
细胞定位
Cytoplasm, cytosol . Nucleus outer membrane . Nucleus, nuclear pore complex . Nucleus inner membrane . Nucleus, nucleoplasm . At steady state it is essentially nucleoplasmic, enriched in nucleoplasmic foci. .
功能
function:Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import.,similarity:Contains 1 NTF2 domain.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
.jpg)
