产品名称
Nrf3 Rabbit Polyclonal Antibody
别名
NFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2, like 3
蛋白名称
Nuclear factor erythroid 2-related factor 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9603
Human Swissprot No.
Q9Y4A8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y4A8/entry
Mouse Swissprot No.
Q9WTM4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WTM4
免疫原
The antiserum was produced against synthesized peptide derived from human NFE2L3. AA range:491-540
特异性
Nrf3 Polyclonal Antibody detects endogenous levels of Nrf3 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009],
组织表达
Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas.
功能
function:Activates erythroid-specific, globin gene expression.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer with MAFG, MAFK and other small MAF proteins that binds to the MAF recognition elements (MARE).,tissue specificity:Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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