产品名称
NPY2-R Rabbit Polyclonal Antibody
别名
NPY2R; Neuropeptide Y receptor type 2; NPY2-R; NPY-Y2 receptor; Y2 receptor
蛋白名称
Neuropeptide Y receptor type 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4887
Human Swissprot No.
P49146
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P49146/entry
Mouse Swissprot No.
P97295
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P97295
免疫原
The antiserum was produced against synthesized peptide derived from human NPY2R. AA range:1-50
特异性
NPY2-R Polyclonal Antibody detects endogenous levels of NPY2-R protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.,
组织表达
High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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