产品名称
NOC2L Rabbit Polyclonal Antibody
别名
NOC2L; NIR; Nucleolar complex protein 2 homolog; Protein NOC2 homolog; NOC2-like protein; Novel INHAT repressor
蛋白名称
Nucleolar complex protein 2 homolog
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26155
Human Swissprot No.
Q9Y3T9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y3T9/entry
Mouse Swissprot No.
Q9WV70
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WV70
免疫原
The antiserum was produced against synthesized peptide derived from human NOC2L. AA range:602-651
特异性
NOC2L Polyclonal Antibody detects endogenous levels of NOC2L protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
NOC2 like nucleolar associated transcriptional repressor(NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008],
组织表达
Brain,Epithelium,Placenta,
细胞定位
Nucleus, nucleoplasm. Nucleus, nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.
功能
similarity:Belongs to the NOC2 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
